PD09 - Association of the TNFα -308 G>A polymorphism with clinical phenotypes of asthma in Moldovan children

نویسندگان

  • Olga Cirstea
  • Liubov Vasilos
  • Ala Cojocaru
  • Dorina Savoschin
  • Tatiana Ivaschenko
  • Mikhail Aseev
  • Dumitru Amoasii
چکیده

Background Patients with asthma show a marked phenotypic variability, suggesting etiological heterogeneity and strong environmental influences. Bronchial asthma is determined by a complex interaction between genetic and environmental factors, but these mechanisms are not yet elucidated. The aim of the study was to evaluate peculiarities of the TNFa gene polymorphism (-308 G>A) incidence and its association with different clinical evolution of bronchial asthma in Moldovan children.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2014